Products · Toothpaste



Swallow-safe caries prevention for infants — the GH12 peptide targets cavity bacteria selectively.
- GH12 peptide targets cavity bacteria selectively
- Safe to swallow for infants
- Xylitol for early caries prevention
How the ingredients work

BUDDY MICROBIES · GH12
A peptide studied against cavity bacteria · In laboratory research · Not a test of this product
- A designed antimicrobial peptide
- Acts on the bacterial membrane
- Measured in laboratory biofilms
Laboratory research on the ingredient. Not a trial of this product, and not a trial in children.
DOI 10.1159/000442898 · DOI 10.1016/j.archoralbio.2017.03.017 · DOI 10.1128/AEM.01423-18

BUDDY MICROBIES · XYLITOL
Bacteria cannot turn xylitol into acid · In laboratory research
- Xylitol is not fermentable
- Less pH drop in biofilm
- Real-time laboratory measurement
Laboratory research. On the ingredient, not on the product.
DOI 10.1016/j.bioflm.2024.100219

BUDDY MICROBIES
A gel with no abrasive
- No abrasive particle
- No foaming agent
- Gel, not paste
Nothing in it to scrub with
Composition fact declared by the brand. Not a safety claim and not a clinical result.
Das Experten · brand specification · ingredient list
Specifications
| Category | Toothpaste · Baby 0+ |
| Best for | 0+ infants · ECC prevention |
| Key ingredient | GH12 peptide + Xylitol |
| Fluoride | Free |
| SLS | Free |
| Standard | German formulation · ISO-certified |
| Vegan | Yes · cruelty-free |
FAQ
Is buddy microbies really safe if my baby swallows it?
Yes — it is formulated to be swallow-safe from 0+, so there is no fluoride-dosing worry if your infant swallows the paste during brushing. It is designed specifically for babies who cannot yet spit.
How does the GH12 peptide prevent cavities without fluoride?
GH12 is an antimicrobial peptide that targets cavity-causing bacteria selectively, reducing the microbial load that drives early childhood caries (ECC) rather than broadly killing the whole oral microbiome. The Xylitol adds a second, non-fluoride line of early caries prevention.
When should I start using it — my baby only has one or two teeth?
It is made for 0+ infants, so you can begin as soon as the first tooth appears (and gently on the gums before that). Early use targets ECC before decay has a chance to establish.
What makes this different from a regular baby toothpaste?
Most baby pastes rely on either low-dose fluoride or are purely cosmetic; buddy microbies pairs the GH12 peptide, which acts selectively on cavity bacteria, with Xylitol for prevention — a swallow-safe, fluoride-free approach built for infants.
Customer reviews
Customer experiences are personal; results vary. Reviews are not medical advice.
Now my kids refuse to brush with any other paste. The result is obvious: the dark spot on my older child's teeth is gone — that says everything about its real quality. As a mum, I'm delighted.
Their little teeth were free of plaque from the very first brushing. A wonderful paste — the kids loved it!
A great paste — my child brushes with real pleasure. And I feel at ease knowing the formula is safe, because a little one is bound to swallow some.
We brush without tears or tantrums — my son loves the strawberry flavour. The formula is clean and safe.
Lovely taste and the little-germ characters make it so much easier to convince my daughter. I show her the germs, tell her we need to chase them away, and now she happily brushes all by herself.
We've been using it for 4 years now, almost since my son first started brushing. We tried other pastes but always came back to this one. It's excellent!



